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Synthesis of Gemcitabine Analogues as Potential Antitumor Agents.

✍ Scribed by Yili Ding


Publisher
John Wiley and Sons
Year
2007
Weight
17 KB
Volume
38
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of Some 5
✍ F. GIRARD; S. LEONCE; L. A. AGROFOGLIO πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB πŸ‘ 1 views

Synthesis of Some 5'-Thiopentofuranosylpyrimidines as Potential Antitumor Agents. -The synthesis of 5'-sulfur-substituted thymidine analogues is achieved by nucleophilic displacement of the 5-chloro derivative (II) and subsequent oxidations and catalytic hydrogenations. None of these compounds show