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Synthesis of fused thiazolo[3,2-a]pyrimidinones: N-aryl-2-chloroacetamides as doubly electrophilic building blocks

✍ Scribed by Janardhan, Banothu; Srinivas, Basavoju; Rajitha, Bavantula; Peter A., Crooks


Book ID
121433647
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
523 KB
Volume
55
Category
Article
ISSN
0040-4039

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The active ester N-fmoc-3-O-[Ac4-Ξ±-D-Man
✍ Anita Ma. Jansson; Morten Meldal; Klaus Back πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier Science 🌐 French βš– 276 KB

The active ester ilP-Rnoc-3-o\_IAc~~-o-Manp-(l~2)-Ac~ar-D-Manpl-J-~r-O-Pfp (6) was synthesized by direct condensation of Aqor-D-Mmp-(l-2)-Ac=ar-D-h&p-Br (4) with l+noc-Thr-0-m (5) and used as a buikiing block in an automated continwus-flow solid-phase synthesis of an 0-glycosylated heptadeca amino a