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Synthesis of Functionalized Tetrahydro-4-oxoindeno[1,2-b]pyrroles from Ninhydrin, Acetylenedicarboxylates, and Primary Amines

✍ Scribed by Issa Yavari; Samereh Seyfi; Manijeh Nematpour; Zinatossadat Hossaini

Book ID: 102255574
Publisher: John Wiley and Sons
Year: 2010
Tongue: German
Weight: 155 KB
Volume: 93
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.200900408

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✦ Synopsis

Abstract

A one‐pot synthesis of dialkyl 1,3a,4,8b‐tetrahydro‐3a,8b‐dihydroxy‐1‐alkyl‐4‐oxoindeno[1,2‐b]pyrrole‐2,3‐dicarboxylates via three‐component reaction from indan‐1,2,3‐trione hydrate (ninhydrin), primary amines, and dialkyl acetylenedicarboxylates is described.

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