The Synthesis of a Multiblock Osteotropi
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Christopher D. Hein; Xin-Ming Liu; Fu Chen; Diane M. Cullen; Dong Wang
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Article
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2010
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John Wiley and Sons
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English
⚖ 685 KB
## Abstract The design and synthesis of a novel bone‐targeting polyrotaxane delivery system that utilizes alendronate (ALN) as targeting moiety is presented in this manuscript. For the introduction of ALN, it is first conjugated to α‐cyclodextrin (α‐CD) and subsequently threaded onto a short poly(e