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Synthesis of fluoromethyl-containing analogs of antitumor alkaloid luotonin A

โœ Scribed by A. S. Golubev; V. O. Bogomolov; A. F. Shidlovskii; L. G. Dezhenkova; A. S. Peregudov; A. A. Shtil; N. D. Chkanikov


Publisher
Springer
Year
2010
Tongue
English
Weight
369 KB
Volume
59
Category
Article
ISSN
1573-9171

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Microwave-assisted rapid synthesis of th
โœ J.S Yadav; B.V.S Reddy ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 133 KB

The total synthesis of the cytotoxic alkaloid luotonin A has been achieved for the first time in high yields by the cyclocondensation of 3-oxo-1H-pyrrolo [3,4-b]quinoline with isatoic anhydride in solvent-free conditions under microwave irradiation.