Microwave-assisted rapid synthesis of the cytotoxic alkaloid luotonin A

✍ Scribed by J.S Yadav; B.V.S Reddy

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 133 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(02)00135-1

✦ Synopsis

The total synthesis of the cytotoxic alkaloid luotonin A has been achieved for the first time in high yields by the cyclocondensation of 3-oxo-1H-pyrrolo [3,4-b]quinoline with isatoic anhydride in solvent-free conditions under microwave irradiation.