𝔖 Bobbio Scriptorium
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Synthesis of Flavin-Containing Model Compounds for DNA Photolyase Mediated DNA Repair

✍ Scribed by Dr. Thomas Carell; Robert Epple; Dr. Volker Gramlich


Book ID
102727039
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
531 KB
Volume
35
Category
Article
ISSN
0044-8249

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A (6-4) Photolyase Model: Repair of DNA
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Ultraviolet irradiation of cells causes the formation of a variety of DNA lesions with known mutagenic, carcinogenic, and lethal effects. The main UV lesions are cyclobutane Β± pyrimidine dimers (CPD lesions) formed in a photochemically allowed [2p 2p] cycloaddition and (6-4) photoadducts; the latte