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A (6-4) Photolyase Model: Repair of DNA (6-4) Lesions Requires a Reduced and Deprotonated Flavin

✍ Scribed by Michaela K. Cichon; Simone Arnold; Thomas Carell


Book ID
101369854
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
124 KB
Volume
41
Category
Article
ISSN
0044-8249

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A (6-4) Photolyase Model: Repair of DNA
✍ Michaela K. Cichon; Simone Arnold; Thomas Carell πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 124 KB

Ultraviolet irradiation of cells causes the formation of a variety of DNA lesions with known mutagenic, carcinogenic, and lethal effects. The main UV lesions are cyclobutane Β± pyrimidine dimers (CPD lesions) formed in a photochemically allowed [2p 2p] cycloaddition and (6-4) photoadducts; the latte