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Synthesis of Five-Membered Cyclic Ethers by Reaction of 1,4-Diols with Dimethyl Carbonate

✍ Scribed by Dr. Fabio Aricò; Prof. Pietro Tundo; Dr. Andrea Maranzana; Prof. Glauco Tonachini


Book ID
112071629
Publisher
Wiley (John Wiley & Sons)
Year
2012
Tongue
English
Weight
567 KB
Volume
5
Category
Article
ISSN
1864-5631

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## Abstract The 1,3‐dipolar cycloaddition reactions of chiral five‐membered cyclic azomethine ylides, generated in situ from ethyl glyoxylate and protected (3__S__,4__S__)‐dihydroxypyrrolidines **3** and **6** have been studied. The facial selectivity of the cycloaddition reaction is governed by th