In the title compound, C~16~H~14~N~4~O~5~, the benzene ring of the nicotinate residue is inclined at an angle of 64.06 (10)° to the benzene ring of the nitrophenoxy group. The molecules are linked by two intermolecular C—H...O and N—H...N hydrogen bonds into a complex three-dimensional framework str
Synthesis of ethyl 5-cyano-6-hydroxy-2-methyl-4-(1-naphthyl)-nicotinate
✍ Scribed by Yongchang Zhou; Tatsuro Kijima; Shunsuke Kuwahara; Masataka Watanabe; Taeko Izumi
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- French
- Weight
- 174 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
A novel ethyl 5-cyano-6-hydroxy-2-methyl-4-(1-naphthyl)-nicotinate is successfully synthesized and the structure is determined by XRD, GC-MS analysis, element analysis and NMR spectroscopic in detail. A reaction mechanism for the reaction is proposed.
📜 SIMILAR VOLUMES
The title compound, C 18 H 18 N 2 O 5 , was synthesized from 2,3dimethoxyphenylmethylidenemalononitrile and ethyl acetoacetate in the presence of triethylbenzylammonium chloride in an aqueous medium. The pyridone and benzene rings make a dihedral angle of 63.8 (1) . There are intermolecular C-HÁ Á Á