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Synthesis of ethyl 3-cyano-2-methylcinnamates and 3-cyano-2-methylcinnamonitriles from the Baylis–Hillman acetates

✍ Scribed by Yun Mi Chung; Ji Hyeon Gong; Taek Hyeon Kim; Jae Nyoung Kim


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
68 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis


The reaction of the DABCO salts 2, generated in situ from the Baylis-Hillman acetates 1, and KCN in aqueous THF gave ethyl 3-cyano-2-methylcinnamates 4a-d and 3-cyano-2-methylcinnamonitriles 4e-f in good yields.


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