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Synthesis of (−)-Epicatechin 3-(3-O-Methylgallate) and (+)-Catechin 3-(3-O-Methylgallate), and Their Anti-Inflammatory Activity

✍ Scribed by Takashi Iijima; Yoshihiro Mohri; Yasunao Hattori; Atsushi Kashima; Tsunashi Kamo; Mitsuru Hirota; Hiromasa Kiyota; Hidefumi Makabe


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
173 KB
Volume
6
Category
Article
ISSN
1612-1872

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## Abstract Methyl 3‐azido‐5‐__O‐tert__‐butyldiphenylsilyl‐2,3‐dideoxy‐D‐__erythro__‐furanoside (3) was coupled with silylated 5‐hydroxymethyluracil (1a) and its C~1~‐C~6~ alkyl ethers 1b–g to give the corresponding protected nucleosides 4a‐g which were deprotected with Bu~4~NF to afford 3‐azido nu