A novel stereoselective synthesis of ena
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Hidemi Yoda; Hiroyasu Yamazaki; Kunihiko Takabe
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Article
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1996
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Elsevier Science
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English
⚖ 120 KB
An efficient and novel process is described for the asymmetric synthesis of (2S, 3S, 5R )-1-methyl-5-nonyl-2-(phenylmethyl)-3-pyrrolidinol, (+)-preussin employing reductive deoxygenation of a functionalized quaternary ct-hydroxy N-Boc pyrrolidine obtained by stereocontroUed elaboration of tri-O-benz