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ChemInform Abstract: A Novel Stereoselective Synthesis of Enantiomerically Pure Antifungal Agent, (+)-Preussin (XI).

โœ Scribed by H. YODA; H. YAMAZAKI; K. TAKABE


Book ID
112034126
Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
27
Category
Article
ISSN
0931-7597

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A novel stereoselective synthesis of ena
โœ Hidemi Yoda; Hiroyasu Yamazaki; Kunihiko Takabe ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 120 KB

An efficient and novel process is described for the asymmetric synthesis of (2S, 3S, 5R )-1-methyl-5-nonyl-2-(phenylmethyl)-3-pyrrolidinol, (+)-preussin employing reductive deoxygenation of a functionalized quaternary ct-hydroxy N-Boc pyrrolidine obtained by stereocontroUed elaboration of tri-O-benz