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Synthesis of enantiomerically pure carbocyclic 3′-azido-2′, 3′-dideoxythymidine, a potential anti-aids drug

✍ Scribed by M. Bodenteich; H. Griengl


Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
129 KB
Volume
28
Category
Article
ISSN
0040-4039

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## Abstract A novel class of nucleosides with the C~1~, atom bonded to three hetero atoms was synthesized. 2′‐Thia‐2′,3′‐dideoxycytidine was the pilot compound of this series. (±)‐β‐2′‐Thia‐1′,3′‐dideoxycytidine (6) and (±)‐α‐2′‐thia‐2′,3′‐dideoxycytidine (7) were synthesized from (±)‐3‐mercapto‐1,