Synthesis of E functionalized prenyl orthothioesters
✍ Scribed by Guy Solladié; Valérie Berl
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 189 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
A four-step synthesis of the ardeemin framework by starting from N-2-aminobenzoyl-a-amino esters is described. In the last step, the acid promoted cyclization of the 1,4-anti-4-alkyl-1-(3-indolylmethyl)-2,4-dihydro-1H-pyrazino[2,1-b]quinazoline-3,6-diones occurs irreversible and stereocontrolled.
Enantioselective hydrogenation of several a,% -unsaturated aldehydes and allylic alcohols of sulfur-functionalized prenyl derivatives with bakers' yeast gave bifunctional chiral (S)-and (R)-es-building blocks for terpene synthesis with high enantiomeric excess. Microorganism-or purified enzyme-medi