Synthesis of (E)-1-Propenyl Ketones from Carboxylic Esters and Carboxamides by Use of Mixed Organolithium-Magnesium Reagents. Synthesis of α-Damascone, β-Damascone, and β-Damascenone

✍ Scribed by Charles Fehr; José Galindo

• Publisher: John Wiley and Sons
• Year: 1986
• Tongue: German
• Weight: 488 KB
• Volume: 69
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.19860690127

✦ Synopsis

For a special (intramolecular) case, see [5]. Vol.69 (1986) 229

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The diethylamides corresponding to esters 1-3 are unreactive.

( E ) / ( Z ) % 9:l. We assume that the major silylenol ether 12 formed has the (E)-configuration (see [15]).