## Abstract The 18‐membered Aib‐containing cyclohexapeptides, cyclo(‐Gly‐Aib‐Aib‐Gly‐Aib‐Phe‐) (**22**), cyclo(‐Gly‐Aib‐Phe(2Me)‐Gly‐Aib‐Aib‐) (**24a**), cyclo(‐Gly‐Phe(2Me)‐Aib‐Gly‐Aib‐Aib‐) (**24b**), and cyclo(‐Gly‐Phe(2Me)‐Aib‐Gly‐Aib‐Phe‐) (**25**), have efficiently been synthesized by solutio
Synthesis of Doubly Cross-Linked Cyclic Hexapeptides
✍ Scribed by Patrik D. Bailey; Steven R. Carter; David G.W. Clarke; Gavin A. Crofts; Joanna H.M. Tyszka; Paul W. Smith; Peter Ward
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 298 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Akfrucl.
Cyclic hexapzptides in which the adjacent Ne-nitrogens of cycle-(Lys-Lys-tily)2 arc cross-linked by pxylyl or (CH& units have been prepared. The key steps in the syntheses of these novel types of peptide wcrc the use
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