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Synthesis of DNA Oligomers Possessing a Covalently Cross-Linked Watson–Crick Base Pair Model

✍ Scribed by Hong-Yu Li; Yao-Ling Qiu; Elisabeth Moyroud; Yoshito Kishi

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 127 KB
Volume: 40
Category: Article
ISSN: 0044-8249
DOI: 10.1002/1521-3773(20010417)40:8<1471::aid-anie1471>3.0.co;2-i

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Structural characteristics of Watson-Crick hydrogen-bonded base pairs are displayed by methylene-bridged base pairs of type A. The shown superposition of the X-ray structure obtained for the base pair A (Rib =Et; Rib =Me) over that of a C-G base pair illustrates that A occupies an area similar to th