Synthesis of dispacamide from the marine sponge agelas dispar
β Scribed by Thomas Lindel; Holger Hoffmann
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 174 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The marine natural product dispacamide (1) has been synthesized for the first time starting from 2thiohydantoin (2). A facile one pot conversion of alkylideme thiohydantoins to the corresponding 2-iminoimidazoiones is described employing tert.-butylhydroperoxide (TBHP) in the presence of aqueous ammonia.
π SIMILAR VOLUMES
New glycosphingolipids, named agelasphins (1-S). have been isolated by antitumor and immtmostimulatory bioassay-guided purification from an extract of a marine sponge, Agelas mouritianus. Strongly active agents in agelasphins had characteristic a-galactosylceramide structures, the isolation of which
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