## Abstract The glycosphingolipid (GSL) composition of the marine sponge __Agelas conifera__ was investigated. In addition to three GSLs previous isolated from __Agelas clathrodes__ (2aβ4a), the novel Ξ±βglycosylceramide 1a was isolated as a major component of the GSL mixture, and its structure was
Glycolipids from sponges. IV. Immunomodulating glycosyl ceramides from the marine sponge agelas dispar.
β Scribed by Valeria Costantino; Ernesto Fattorusso; Alfonso Mangoni; Massimo Di Rosa; Angela Ianaro; Pasquale Maffia
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 574 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4020
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The marine natural product dispacamide (1) has been synthesized for the first time starting from 2thiohydantoin (2). A facile one pot conversion of alkylideme thiohydantoins to the corresponding 2-iminoimidazoiones is described employing tert.-butylhydroperoxide (TBHP) in the presence of aqueous amm
## Abstract The marine sponge __Agelas clathrodes__ was analyzed for glyβcosphingolipids, and four cerebrosides (1aβ4a) were isolated, each as a mixture of homologs. The structure of the new glycosphingolipid 1a was elucidated by extensive NMR studies of its peracetate and by chemical analysis. The
## Abstract A specimen of the marine sponge __Agelas longissima__ was analyzed for glycosphingolipids. Three cerebrosides 1aβ3a were isolated, each as a mixture of homologs. The structure of the new glycosphingolipid 1a was elucidated by extensive NMR studies of its peracetate derivative and chemic
## Abstract A new 4βsulfated ceramide, ircisulfamide (=__N__β[(1__S__\*,2__S__\*,3__R__\*)β2βhydroxyβ1β(hydroxymethyl)β3β(sulfooxy)heptadecyl]hexadecanamide; **1**), and a new glycosphingolipid, ircicerebroside (=(2__R__\*)β__N__β{(1__S__\*,2__R__\*,3__E__,7__E__)β1β[(__Ξ²__βDβglucopyranosyloxy)meth