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Synthesis of Diheterocyclic Compounds Based on Triazolyl Methoxy Phenylquinazolines via a One-Pot Four-Component-Click Reaction

✍ Scribed by Dabiri, Minoo; Salehi, Peyman; Bahramnejad, Mahboobeh; Sherafat, Fatemeh

Book ID: 126989600
Publisher: American Chemical Society
Year: 2010
Tongue: English
Weight: 348 KB
Volume: 12
Category: Article
ISSN: 1520-4766
DOI: 10.1021/cc100043z

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## Abstract A four‐component reaction for the synthesis of 1,2‐dihydroisoquinoline derivatives is described. The __Huisgen__ 1,4‐dipolar intermediate, which is produced from isoquinoline and an electron‐deficient acetylene compound **1**, reacts with H~2~O in the presence of diketene to produce 1,2