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Synthesis of diethyl N-dodecylphosphoramidate analogs as potential inhibitors of dental plaque

โœ Scribed by Warner, Victor D.; Mirth, Dale B.; Dey, Adrienne S.; Turesky, Samuel S.; Soloway, Barbara

Book ID
124067302
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
278 KB
Volume
16
Category
Article
ISSN
0022-2623

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Synthesis and in vitro evaluation of 8-h
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โœ Victor D. Warner; Joseph D. Musto; Samuel S. Turesky; Barbara Soloway ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 389 KB

Some 4- and 5-substituted 8-hydroxyquinolines, with predicted log P values in the range of 1.48-2.90, were synthesized by modified Skraup reactions or thermal cyclization. These hydroxyquinolines include the 5-methyl, 4,5-dimethyl, 4-methyl, 5-hydroxy-4-methyl, 5-methoxy, 5-methoxy-4-methyl, 4-hydro