Synthesis of dideuteromethylene hydrocarbons by copper catalyzed reaction of grignard reagents

✍ Scribed by Carl A. Elliger

• Publisher: John Wiley and Sons
• Year: 1983
• Tongue: French
• Weight: 234 KB
• Volume: 20
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/jlcr.2580200117

✦ Synopsis

The d i l i t h i u m t e t r a c h l o r o c u p r a t e c a t a l y z e d r e a c t i o n of Grignard r e a g e n t s w i t h long c h a i n a l k y l p -t o l u e n e s u l f o n a t e s p r o v i d e s s p e c i f i c a l l y l a b e l l e d d i d e u t e r o m e t h y l e n e hydroc a r b o n s . The t o s y l a t e esters are r e a d i l y o b t a i n e d by LiAlD4 t r e a t m e n t of f a t t y a c i d m e t h y l e s t e r s f o l l o w e d by t o s y l a t i o n i n p y r i d i n e .