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Synthesis of Diastereomerically and Enantiomerically Pure 2,3-Disubstituted Tetrahydrofurans Using a Sulfoxonium Ylide

✍ Scribed by Schomaker, Jennifer M.; Pulgam, Veera Reddy; Borhan, Babak


Book ID
111952564
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
56 KB
Volume
126
Category
Article
ISSN
0002-7863

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The boron trifluoride promoted condensation of 7Z)-anti-4-hvdroxv-1-alkenvl carbamates and aldehvdes (or k&ones) yields the title Compounds with high two;old diastereofacial selectivity. In all, a new flexible strategy is offered for the construction of cis,trans,trans substituted tetrahydrofurans b