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Synthesis of Deuterium-Labeled Perfume Ingredients as Internal Standards for Their GC/MS Quantification

✍ Scribed by Christian Chapuis; Carole Cantatore; Peter Fankhauser; René Challand; Jean-Jacques Riedhauser

Publisher
John Wiley and Sons
Year
2009
Tongue
German
Weight
279 KB
Volume
92
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

The synthesis of various D‐labeled perfume ingredients (orris‐like, sandalwood‐like, musky, and amber‐like) is presented. These substances, possessing practically identical H~2~O/solid and solid/gas partition coefficients as their unlabeled analogues, are used as internal standards for the validation of a new analytical GC/MS method for the determination of low residual concentrations in H~2~O after biodegradability tests.

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