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Synthesis of deuterated β-carotene

✍ Scribed by H. Robert Bergen III; James A. Olson


Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
202 KB
Volume
27
Category
Article
ISSN
0022-2135

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✦ Synopsis


The synthesis of 10,lO' 19,19 , 19,19' , 19' 19'-2H8p-carotene is described. The double condensation (C15+C o+C15=C40) of the Wittig salt of 9 , 9 , 9 , 10-2H4-pionyliaene ethanol with the symmetrical Cl0 dial 2,7- dimethyl-2 , 4 , 6-octatrienedial led directly to 2H -pcarotene. The symmetrical labelling pattern of this deuterated p-carotene will function as a tracer for the study of ,+carotene metabolism in humans.


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