## Abstract For Abstract see ChemInform Abstract in Full Text.
Synthesis of desmosterol and epidesmosterol from hyodeoxycholic acid
โ Scribed by Kiyoshige Ochi; Isao Matsunaga; Minoru Shindo; Chikara Kaneko
- Book ID
- 119481389
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 474 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0039-128X
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๐ SIMILAR VOLUMES
Typhasterol 2 was synthesized stereoselectively from hyodeoxycholic acid 3. The aldehyde 5 derived from 3 was reacted with the anion of 3-methylbutenolide under kinetic condition to afford (22R,23R)-7 as the major product. Hydrogenation of 7 and its 22-acetate 14 over PtO2-Pt/C yielded the expected
The synthesis of lanosterol [la] and desmosterol [Ira] Iabeled with 14C in the 25 position by a Wittig reaction between triphenyl-214C isopropylidene-phosphorane [IVb] and the corresponding aldehydes are described. The specijic activities obtained are, respectively, 0.539 mClmM and 0.752 mClmM and t