A series of new, 2-substituted 3-aryl-8,9,10,11-tetrahydro-5-methyl[1]benzothieno [3',2' : 5,6]pyrido [4,3-d]pyrimidin-4(3H)-ones, compounds 5a -q, were designed and synthesized via the aza-Wittig reaction as the key step. The iminophosphorane 1 reacted with phenyl isocyanate (or 4-chlorophenyl isoc
Synthesis of Derivatives of Pyrido[4,3-d]pyrimidin-4(3H)-one (IV), (VI) via an Iminophosphorane.
✍ Scribed by Jian-Chao Liu; Hong-Wu He; Qing-Yun Ren; Ming-Wu Ding
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 22 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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## Abstract magnified image The carbodiimides **5**, obtained from reactions of iminophosphorane **4** with aromatic isocyanates, reacted with amines, phenols or ROH to give 2‐substituted 5,6,7,8‐tetrahydropyrido[4′,3′:4,5]thieno[2,3‐__d__]‐pyrimidin‐4(3__H__)‐one 7 in the presence of catalytic am
## Abstract The carbodiimides **4**, obtained from reactions of iminophosphorane **3** with aromatic isocyanates, were reacted with secondary amines to give 2‐dialkylamino‐5‐ethyl‐6‐methyl‐thieno[2,3‐__d__]pyrimidin‐4(3__H__)‐ones **6** in the presence of catalytic amount of EtONa. Reactions of **4
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract A series of new 2‐substituted 3‐(4‐chlorophenyl)‐5,8,9‐trimethylthieno[3′,2′: 5,6]pyrido[4,3‐__d__]pyrimidin‐4(3__H__)‐ones **8** were synthesized __via__ an aza‐__Wittig__ reaction. Phosphoranylideneamino derivatives **6a** or **6b** reacted with 4‐chlorophenyl isocyanate to give carbo