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Synthesis of derivatives of 4-imino-2-amino-2-imidazoline. New example of a multicomponent condensation involving isonitriles

โœ Scribed by A. I. Polyakov; L. A. Medvedeva; O. A. D'yachenko; A. B. Zolotoi; L. O. Atovmyan


Book ID
112356154
Publisher
Springer US
Year
1986
Tongue
English
Weight
570 KB
Volume
22
Category
Article
ISSN
0009-3122

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A novel synthesis of some 2-imino-4-thia
โœ Firouz Matloubi Moghaddam; Leila Hojabri ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 386 KB

An efficient and simple route is presented to the synthesis of some iminothiazolidinone derivatives. ฮฑ-Chloro amide derivatives undergo coupling reaction with isothiocyanate in the presence of a mild base, followed by nucleophilic substitution of chlorine by the sulfur atom of isothiocyanate.