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Synthesis of D3-sulpiride and its (R) and (S) isomers

✍ Scribed by M. Al-koutayni-rifai; G. Jamet; R. R. Kerr; L. Jung; J. C. Koffel

Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
419 KB
Volume
27
Category
Article
ISSN
0022-2135

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✦ Synopsis

Racemic dg-sulpiride, (R)-(+)-dg-sulpiride and (S)-(-)-dg-sulpiride (with three deuterium atoms in the methoxy function ortho to the benzamide), as well as (R)-(+)-sulpiride and (S)-(-)-sulpiride were synthesized. The structures were characterized by melting points, IR, 1H-NMR, GC-MS and polarimetry. The measured [a$?vas 65O in 5% DMF.

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