Synthesis of d-galacto-1-deoxynojirimycin (1,5-dideoxy-1,5-imino-d-galactitol) starting from 1-deoxynojirimycin
β Scribed by Fred-Robert Heiker; Alfred Matthias Schueller
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 373 KB
- Volume
- 203
- Category
- Article
- ISSN
- 0008-6215
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The title, 1,5-dideoxy-l,5-imino-D-arabinitol (2), was synthesized in seven steps from Darabinose with 5-azido-5-deoxy-o-arabinofuranose as key intermediate and 40% overall yield. An affinity procedure employing the N-carboxypentyl derivative of 2 linked to aminohexyl agarose permitted the isolation