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Synthesis of Cyclobutane Nucleosides

✍ Scribed by Ebead, Abdelaziz; Fournier, Rene; Lee-Ruff, Edward


Book ID
120464259
Publisher
Taylor and Francis Group
Year
2011
Tongue
English
Weight
780 KB
Volume
30
Category
Article
ISSN
0732-8311

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Versatile and highly efficient synthetic routes leading to optically active cyclobutanones, g-amino acids and d-amino alcohols are described. These compounds are relevant synthetic precursors to enantiopure cyclobutane carbocyclic nucleosides and oligopeptides. (-)-(S)-Verbenone is the chiral starti