The transannular cyclization of (Z,Z)-1-hydroxy-cyclonona-2,6-diene by iodonium assisted oxirane ring expansion was studied. The regioselectivity for the 14.3.11 vs t5.2.11 lo-oxabicyclo decane skeletons is high, and the iodine addition is also highly trans-selective. The results are rationalized in
β¦ LIBER β¦
Synthesis of cyclic ethers via bromine assisted epoxide ring expansion
β Scribed by Davies, Stephen G.; Polywka, Mario E. C.; Thomas, Susan E.
- Book ID
- 120226827
- Publisher
- Royal Society of Chemistry
- Year
- 1986
- Weight
- 610 KB
- Category
- Article
- ISSN
- 1472-7781
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