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Synthesis of Cyclic Ether via an Intramolecular Barbier Reaction of Iodo Ester with Butyllithium.

✍ Scribed by Tatsuo Saito; Toshiharu Takeuchi; Miyuki Matsuhashi; Tadashi Nakata


Publisher
John Wiley and Sons
Year
2007
Weight
35 KB
Volume
38
Category
Article
ISSN
0931-7597

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πŸ“œ SIMILAR VOLUMES


A New Enantioselective Total Synthesis o
✍ Wolfgang Oppolzer; Hartmut Hauth; Paul PfΓ€ffli; Roland Wenger πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 German βš– 615 KB

## Abstract Natural Vincamine (**1**) has been synthesized in an enantioselective manner starting from the ethylpentenal **7**. In the key step a mixture of the diastereoisomeric racemates, **14** and **15**, was directly obtained from the silyl enol ether **11** and the dihydro‐β‐carboline **12**