𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of Conformationally Locked Carbohydrates: A Skew-Boat Conformation of L-Iduronic Acid Governs the Antithrombotic Activity of Heparin

✍ Scribed by Sanjoy K. Das; Jean-Maurice Mallet; Jacques Esnault; Pierre-Alexandre Driguez; Philippe Duchaussoy; Philippe Sizun; Jean-Pascal Hérault; Jean-Marc Herbert; Maurice Petitou; Pierre Sinaÿ


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
111 KB
Volume
40
Category
Article
ISSN
0044-8249

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis of Conformationally Locked l-I
✍ Sanjoy K. Das; Jean-Maurice Mallet; Jacques Esnault; Pierre-Alexandre Driguez; P 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 298 KB 👁 2 views

We have used organic synthesis to understand the role of liduronic acid conformational flexibility in the activation of antithrombin by heparin. Among known synthetic analogues of the genuine pentasaccharidic sequence representing the antithrombin binding site of heparin, we have selected as a refer