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Synthesis of condensed derivatives of 2-substituted thieno[2,3-d]pyrimidin-4-ones

✍ Scribed by S. G. Kazaryan; A. S. Noravyan; G. A. Gevorkyan

Publisher: Springer US
Year: 1999
Tongue: English
Weight: 211 KB
Volume: 35
Category: Article
ISSN: 0009-3122
DOI: 10.1007/bf02252109

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ChemInform Abstract: Synthesis of Conden

ChemInform Abstract: Synthesis of Condensed Derivatives of 2-Substituted Thieno[2,3-d]pyrimidin-4-ones.

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Derivatives of Condensed Thieno[2,3-d]py

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Convenient synthesis of substituted 2-(2

Convenient synthesis of substituted 2-(2-iminocoumarin-3-yl)thieno[2,3-d]pyrimidin-4-ones

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## Abstract magnified image The interaction of both 2‐iminocoumarin‐3‐carbonitriles and 2‐iminocoumarin‐3‐carbothioamides with 2‐aminothiophen‐3‐carboxamides lead to formation of 3‐(4‐oxo‐3,4‐dihydrothieno[2,3‐__d__]pyrimidin‐2‐yl)‐2‐iminocoumarins in two steps. The simplicity of the procedure, as

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Efficient synthesis of 2-substituted thi

Efficient synthesis of 2-substituted thieno[2,3-d]pyrimidin-4(3H)-ones via an iminophosphorane

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## Abstract The carbodiimides **4**, obtained from reactions of iminophosphorane **3** with aromatic isocyanates, were reacted with secondary amines to give 2‐dialkylamino‐5‐ethyl‐6‐methyl‐thieno[2,3‐__d__]pyrimidin‐4(3__H__)‐ones **6** in the presence of catalytic amount of EtONa. Reactions of **4