Synthesis of cis-Isoquinolonic Acids Containing Boronate Esters.
β Scribed by Haiwen Zhang; Christopher M. Vogels; Susan L. Wheaton; Felix J. Baerlocher; Andreas Decken; Stephen A. Westcott
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 15 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Sulfonamides containing pinacol pro- tected boronate ester groups have been prepared by the addition of H 2 NC 6 H 4 Bpin (pin = O 2 C 2 Me 4 ) to sulfonyl chlorides p-RC 6 H 4 SO 2 Cl (R = CH 3 , NO 2 ). Hydrogenation of the nitro derivatives afford the corresponding sulfanilamides without compromi
## Abstract We have prepared a series of novel 2,3βdihydroβ4βpyridones containing boronate esters using the aza DielsβAlder reaction with Danishefsky's diene and imines derived from formylphenylboronic acids. This reaction can be carried out in moderate to high yields using Yb(OTf)~3~ as a Lewis ac