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Synthesis of cis-Isoquinolonic Acids Containing Boronate Esters.

✍ Scribed by Haiwen Zhang; Christopher M. Vogels; Susan L. Wheaton; Felix J. Baerlocher; Andreas Decken; Stephen A. Westcott


Publisher
John Wiley and Sons
Year
2006
Weight
15 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract We have prepared a series of novel 2,3‐dihydro‐4‐pyridones containing boronate esters using the aza Diels–Alder reaction with Danishefsky's diene and imines derived from formylphenylboronic acids. This reaction can be carried out in moderate to high yields using Yb(OTf)~3~ as a Lewis ac