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Synthesis of chiral β-amino sulfides and β-amino thiols from α-amino acids

✍ Scribed by Graeme A. Cran; Colin L. Gibson; Sheetal Handa


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
227 KB
Volume
6
Category
Article
ISSN
0957-4166

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Synthesis of optically active α,β-disubs
✍ Gmeiner, Peter ;Hummel, Evi ;Haubmann, Christian 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 695 KB

## Abstract Starting from the enantiomerically pure building block 2 which is readily available from D‐asparagine α,β‐disubstituted β‐amino nitriles and β‐amino acids could be synthesized. After deprotonation of the nitrile α‐position the introduction of substituents was performed by alkylation of