Synthesis of Chiral Pyridylphenols for the Enantioselective Addition of Diethylzinc to Aldehydes
β Scribed by Pei-Shan Wu; Chinpiao Chen
- Book ID
- 112120317
- Publisher
- Chinese Electronic Periodical Services
- Year
- 2012
- Tongue
- English
- Weight
- 973 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0009-4536
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π SIMILAR VOLUMES
Optically active ferrocenyl amino alcohols have been prepared from commercially available L-alaninol, L-leucinol and L-valinol. They have been utilized as chiral ligands in the catalytic addition of diethylzinc to aldehydes. The influence of the substituents on the stereogenic centers of the ligand
## Abstract For Abstract see ChemInform Abstract in Full Text.
Optically active amino thioacetate derivatives of (+l-norephedrine were found to act as effective catalysts for enantioselective addition of diethylzinc to aldehydes. This reaction provided optically active secondary alcohols with e.e. of up to >99%.