Synthesis and reduction of chiral sulfin
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M.C. CarreΓ±o; J.L.GarcΓa Ruano; A. Rubio
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Article
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1987
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Elsevier Science
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French
β 264 KB
The reaction of cyclohexanone with (S)-(-)-menthyl-p-toluenesulfinate in the presence of Pr@gBr yields a mixture of enantiomerically pure 2-p-tolylsulfinylcyclohexanone diastereoisomers. Their stereoselective reduction to chiral hydroxysulfoxides is also reported. The important role of chiral 8-ket