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Synthesis of Chiral C/N-Functionalized Morpholine Alcohols: Study of Their Catalytic Ability as Ligand in Asymmetric Diethylzinc Addition to Aldehyde.

✍ Scribed by Rajesh Dave; N. Andre Sasaki


Publisher
John Wiley and Sons
Year
2006
Weight
27 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract Optically active new pyridyl alcohols **1–4**, which can be easily synthesized by the reaction of (+)‐camphor or (βˆ’)‐menthone with lithiated pyridine derivatives, were applied as chiral ligands in the asymmetric addition of diethylzinc to aldehydes. Good yields with up to 94.0%enantiome