In this article, we have described the asymmetric cyclization of L-serinoates and N-benzyl Lserinoate with phosphoro(no-)dichloridates or their thio-analog, respectively, and we have investigated the asymmetric induction effect of the chiral carbon center on the forming of a chiral phosphorus center
Synthesis of Chiral 2-OXO- and 2-THIO-1,3,2-Oxazaphospholidines via the Asymmetric Cyclization of L-Serinoates with (Thio)Phosphoryl Dichlorides
β Scribed by He, Zheng-Jie; Chen, Wen-Bin; Zhou, Zheng-Hong; Tang, Chu-Chi
- Book ID
- 121350709
- Publisher
- Taylor and Francis Group
- Year
- 2000
- Tongue
- English
- Weight
- 245 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0039-7911
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract In order to search for novel antitumor and antiviral agents with high activity and low toxicity, a series of chiral 2βthio(oxo)β1,3,2βoxazaphospholidines were synthesized via the reaction of Lβmethionol with all kinds of (thio)phosphoryl dichlorides in THF in the presence of triethylami