𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of Cephalostatin Analogues by Symmetrical and Non-Symmetrical Routes

✍ Scribed by Michael Drögemüller; Timo Flessner; Rolf Jautelat; Ulrich Scholz; Ekkehard Winterfeldt

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
422 KB
Volume
1998
Category
Article
ISSN
1434-193X

No coin nor oath required. For personal study only.

✦ Synopsis

The synthesis of the cephalostatin-analogous bis-steroidal pyrazines by coupling of enamino ketones (5, 40) with vinyl azides (17a/b) is reported. Furthermore, an improved pyrazines 6, 27a/b and 41 by the transformation of the C 2symmetrical diketone 6 as a central precursor, as well as the procedure for preparation of the diketone 6 described earlier is presented. direct preparation of several non-symmetrical bis-steroidal

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Cephal
ChemInform Abstract: Synthesis of Cephalostatin Analogues by Symmetrical and Non-Symmetrical Routes.
✍ Michael Droegemueller; Timo Flessner; Rolf Jautelat; Ulrich Scholz; Ekkehard Win 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

Synthesis of Cephalostatin Analogues by Symmetrical and Non-Symmetrical Routes. -Title analogues as (I), (II) and (III) are synthesized either via two approaches: 1. a symmetrical route by regioselective, but not substrate-specific condensation of enamino ketones as in case of (I), followed (if des