Synthesis of CD-ring structure of cortistatin A, an anti-angiogenic steroidal alkaloid from marine sponge
β Scribed by Naoyuki Kotoku; Yuji Sumii; Takeshi Hayashi; Motomasa Kobayashi
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- French
- Weight
- 187 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0040-4039
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## Abstract Two stereoisomers of penazetidine A (1a), the azetidine alkaloid isolated from the IndoβPacific marine sponge __Penares sollasi__, were synthesized by starting from (__S__)βserine and (__R__)βor (__S__)βcitronellol. The natural penazetidine A must be either (2__S__,3__R__,4__S__,12β²__R_