Synthesis of carboxylic acid derivatives of triphenylphosphine cyanoborane
✍ Scribed by Patty Wisian-Neilson; Mark A. Wilkins; F. Chandler Weigel; Christopher J. Foret; Donald R. Martin
- Book ID
- 115976699
- Publisher
- Elsevier Science
- Year
- 1981
- Weight
- 216 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0022-1902
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## Abstract This paper describes the synthesis of several new 2,3‐dimethoxy‐6‐methyl‐7‐nitro‐quinoxaline‐5‐carboxylic acid derivatives (13a‐m) __via__ a multistep synthetic route from 5‐methyl‐1__H__‐benzo[__d__][1,3]oxazine‐2,4‐dione (1).
A series of tricyclohexyland triphenylphosphine boranes, cahoxyboranes and cyanoboranes were synthesized These compounds have potent hypolipidemic effects, antineoplastic and antiinflammatory activities in rodents. Furthermore, they demonstrated potent cyctotoxicity against standard human tissue cu