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Synthesis of carbon-14 and deuterium labeled N-nitroso-2(3′,7′-dimethyl-2′,6′-octadienyl)aminoethanols

✍ Scribed by S. L. Abidi; U. S. Fish; Wildlife Service; A. L. Idelson

Publisher
John Wiley and Sons
Year
1981
Tongue
French
Weight
412 KB
Volume
18
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Methods of preparation of carbon‐14 and deuterium labeled N‐nitroso‐2(3′,7′‐dimethyl‐2′,6′‐octadienyl)aminoethanols are described. The primary synthetic method involved alkylation of ethanolamine or ethylglycine with suitable chlorides and subsequent mild nitrosation. Isomeric ^14^C‐nitrosamines were also prepared by selective α‐cleavage of the di‐substituted ethanolamine with nitrous acid.

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