D-Glucose was converted to a backbone chain containing the appropriate functionalities an correc7 stereochemistry for the construction of the Cl-C9 fragment of the 16-membered ring macrolide antibiotics carknycin A and B and leuccqzin A3. Ieucctnycin AS and carkmycins A and B (magnamycins A and B) s
Synthesis of carbomycin B. Introduction of the amino disaccharide onto the 16-membered-ring aglycone
β Scribed by Tatsuta, Kumiaki; Tanaka, Akihiro; Fujimoto, Koichi; Kinoshita, Mitsuhiro; Umezawa, Sumio
- Book ID
- 127114244
- Publisher
- American Chemical Society
- Year
- 1977
- Tongue
- English
- Weight
- 261 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
Segments i (Cll-C17) and ii (Cl-ClO), synthesized from D-glucose by employing some stereoselective reactions and benzyl-type protecting groups, were esterified and cyclized to the 16-membered enone, which was readily converted to tylonolide, the aglycone of tylosin. Tylosin is a typical 16-membered
A 16+15 membered bicyclic polypeptide containing biaryl ether bonds, model of A-O-C-B-O-D rings of kistamicin has been synthesized by sequential intramolecular SNAr reactions.
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