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Synthesis of C-ring-functionalized A-ring-aromatic trichothecane analogs

โœ Scribed by Anderson, Wayne K.; Lee, George E.


Book ID
119961146
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
947 KB
Volume
45
Category
Article
ISSN
0022-3263

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Total synthesis of 4-deoxyverrucarol (4), a trichothecane-type sesquiterpene was achieved via two types of ring expansion reaction, 1,2-rearrangement of 18 and palladium mediated ring expansion reaction of 20, as key steps providing a new route to trichothecanes.