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Synthesis of C-3 side-chain carboxylic acid cannabinoid derivatives

✍ Scribed by Ronald F. Borne; Scott C. Mauldin


Book ID
112127860
Publisher
Journal of Heterocyclic Chemistry
Year
1985
Tongue
English
Weight
350 KB
Volume
22
Category
Article
ISSN
0022-152X

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A new route towards the asymmetric preparation of quaternary 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives has been developed. The key step involves an intramolecular Pictet-Spengler reaction of an oxazolidino ester.